The Uncertainty principle doesn’t state that we humans cannot measure with absolute precision certain pairs of physical properties of a particle.

It states that it is not possible. The “we” factor is not included in the Heisenberg’s uncertainty principle. The idea behind is that a measure will interact with the particle we want to measure, altering it’s state and making impossible to know the state as it was.

Of course we should define what a “measure” is. It is a mathematical concept that involves matrix and not very simple to understand… at least for me. Anyway physics use mathematics, that’s why a measure is a mathematical artifact.

It seems that “nature” is intrinsically non deterministic. That means that given the same exact initial conditions and same (physics) laws, the outcome of what will happen will likely not be the same.

It also means that the future is not predictable precisely, there is space for “free will”.

Finally, there is a confusion between nothingness and emptiness. Time/space is full of intrinsic energy, and this is the very essence of existence. Matter is just a state of energy.